The exact pathophysiology of intrinsic rhinitis is not fully understood. The generally held belief is that
it is due to an imbalance between the outflow of the nasal sympathetic and parasympathetic nervous systems, perhaps due to excessive parasympathetic or reduced sympathetic activity. In this study the nasal airway response to a predominantly sympathetic stimulus, isometric exercise, was studied in 19 patients with intrinsic rhinitis and compared with 16 normal patients.
The study shows that there is an abnormal response to isometric exercise in intrinsic rhinitis, perhaps
due to relative nasal sympathetic hyposensitivity.
The nasal response to isometric exercise in non-eosinophilic intrinsic rhinitis
- A. D. WILDE11Department of Otolaryngology, Royal Liverpool University Hospital, Liverpool, UK, 22Mr A. Wilde, Department of Otolaryngology, Royal Liverpool University Hospital, Prescott Street, Liverpool, L69 3BX, UK.,
- J. A. COOK11Department of Otolaryngology, Royal Liverpool University Hospital, Liverpool, UK and
- A. S. JONES11Department of Otolaryngology, Royal Liverpool University Hospital, Liverpool, UK
- 1Department of Otolaryngology, Royal Liverpool University Hospital, Liverpool, UK
2Mr A. Wilde, Department of Otolaryngology, Royal Liverpool University Hospital, Prescott Street, Liverpool, L69 3BX, UK.
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2273.1996.tb01031.x?journalCode=coa